5. Sinaloa Cartel
Revenue: $3 billion
The notorious gang that El Chapo hails from, the Sinaloa Cartel has become Mexico’s largest drug cartel. Many of the Mexican cartels serve as the middlemen for South American drug producers and American consumers. It is estimated that Americans spend $100 billion each year on drugs and it’s estimated that $6.5 billion makes its way to Mexican cartels, and about $3 billion of that goes to the Sinaloa Cartel.