On Seinfeld: Bryan Cranston played Tim Whatley, Jerry’s dentist responsible for some of the most memorable moments on the show.
On Seinfeld: As Linette, Amanda Peet’s lifestyle was so hard to keep up with, Jerry had to employ George as his dating assistant.
On Seinfeld: Catherine Keener’s character is responsible for one of the most remarkable works of art of the 20th century: The Kramer.
On Seinfeld: Christine Taylor was another of Jerry’s girlfriends. Her problem: Though she seemed perfect in just about every way except for having few friends Jerry suspects he’s dating a loser. Jerry’s parents approval confirms this suspicion for him.
On Seinfeld: Jerry eventually gets engaged (to Janeane Garofalo) during the show’s nine-season run, but the closest he ever came to being a husband was when he and Courteney Cox’s character pretended to be married for a dry cleaning discount.
Daniel Dae Kim
On Seinfeld: As a med student, Daniel Dae Kim nails the gonorrhea diagnosis thanks to Kramer’s dramatic storytelling and inflamed urethra.
On Seinfeld: Jerry swooped right in after Debra Messing’s character’s separation, only to find out that she was a racist anti-Semite.
David James Elliott
On Seinfeld: David James Elliott plays the hunky mover who Elaine falls for at first sight.
On Seinfeld: Denise Richards’ character almost cost Jerry and George their chance at a TV pilot. She played the daughter of NBC’s head of programming whose low-cut shirt was a little too distracting for George. (“Get a good look, Costanza?!”)
On Seinfeld: Jane Leeves played Marla, the one virgin Jerry dates until she finds out about the infamous “contest,” at which point she runs off with John F. Kennedy, Jr.
On Seinfeld: Jennifer Coolidge’s character tortured Jerry by not giving him a massage even though she was a massage therapist. Obviously, he had to break up with her.
On Seinfeld: Jeremy Piven’s audition for the part of George in their pilot hit a little too close to home for Georgie boy. Maybe it was the sweats.
On Seinfeld: Anna Gunn played Amy, one of Jerry’s ill-fated girlfriends. After mistakenly thinking she’s cheating on him thanks to George’s alleged squinting prowess, their relationship ends.
On Seinfeld: Before Napoleon Dynamite, Jon Gries was the resident homeless guy in the Seinfeld universe. He steals Kramer and Newman’s rickshaw, doesn’t return Tupperware, and finds a second home for George’s toupee when Elaine hurls it from Jerry’s apartment.
On Seinfeld: Like many women on the show, Kristin Davis’ run as Jerry’s girlfriend was short-lived because Jerry couldn’t get over one tiny issue: She unknowingly used a toothbrush he accidentally dropped in the toilet.
On Seinfeld: Remember the days of speed-dial? That was at the center of Jerry’s relationship with Lauren Graham’s character. Jerry could judge how their relationship was going based on his position on speed dial. When he beats out her step-mother, things get very Mrs. Robinson-y.
On Seinfeld: George blows it with Lisa Edelstein because he’s too concerned with the fact that Jerry’s girlfriend can’t stand him.
On Seinfeld: A clown who doesn’t know who Bozo is? That was Jon Favreau as the disappointingly named Eric the Clown in “The Fire” episode.
On Seinfeld: Unaware dermatologists treat skin cancer, Jerry is convinced Dr. Sara Sidarides (Marcia Cross) is exaggerating when she says she “saves lives.” She breaks up with him after he calls her “pimple popper M.D.” (obviously).
On Seinfeld: Mariska Hargitay was almost the Elaine on the show within the show. While casting their NBC pilot, she comes in to audition for the part and Jerry, clearly, is more than willing to run lines with her.
On Seinfeld: Megan Mullally’s role as George’s girlfriend was cut short thanks to a question of chip etiquette. When her character’s brother found George double-dipping, it was over.
On Seinfeld: In “The Muffin Tops” Melinda Clarke plays another of Jerry’s girlfriends, who falls under the impression he’s naturally hairless.
On Seinfeld: Molly Shannon was ready to scrap on her episode of Seinfeld. She was the one who wouldn’t swing her arms when she walked which lead to the infamous “cat fight” with Elaine.
On Seinfeld: Things take a turn for the worse when Peter Krause turns out to be a white supremacist liaison and pulls a gun on Jerry and the gang in the back of a limo.
On Seinfeld: In 1993, Teri Hatcher’s body was so smoking hot, it made Jerry question just how natural some parts of it were. Then he found out: “They’re real and they’re spectacular.”